mutation
mutation — noun
1. a biological process that permanently alters the DNA sequence inside a cell, oft
a biological process that permanently alters the DNA sequence inside a cell, often creating new or changed traits in a living thing
A mutation in the BRCA1 gene raises the risk of developing breast cancer.
mutation in [gene] + raises risk of [disease]
The research team studied how UV radiation causes genetic mutation in rice crops.
cause + genetic mutation in [organism]
Baraka's latest project looks at beneficial mutations that help bacteria survive antibiotics.
Most mutations happen naturally when cells copy their DNA during division.
- genetic alteration
more specific; often used in clinical contexts
- gene change
simpler, everyday language for the same process
文法句型
mutation in [gene/organism]
cause/undergo mutation
用法筆記
Countable when referring to a specific instance (a mutation in the gene); uncountable when discussing the general process (mutation occurs constantly). Subject is often a gene, organism, or environmental factor (radiation, chemicals).
常見錯誤
2. a living thing whose DNA has undergone a permanent change, or a body feature tha
a living thing whose DNA has undergone a permanent change, or a body feature that appeared as a result of such a change
The white peacock at the city zoo was a rare genetic mutation.
describing an organism as a mutation
Farmers selected this mutation of wheat because it naturally resists fungus.
Hui found a mutation of the tomato plant that produced fruit twice as large.
The six-fingered trait in that family line is a harmless genetic mutation.
文法句型
be/become a mutation
a mutation of [species]
用法筆記
Unlike sense 1 (the process), this sense refers to the result — the changed organism or the trait itself. Often used with 'of' to specify the original species: a mutation of the common fruit fly.
常見錯誤
3. a major change in the shape, structure, or character of something that is not a
a major change in the shape, structure, or character of something that is not a living thing
The English language underwent a significant mutation after the Norman invasion.
undergo a mutation — for abstract change
Sofie noticed a mutation in the company's office culture after the new director arrived.
A sudden mutation in public opinion forced the minister to resign.
The software went through several mutations before reaching its final design.
- transformation
suggests a more complete change of form; often positive
- shift
less dramatic; can be small or large
- alteration
less formal; can be minor or reversible
- stability
the state of not changing
- preservation
keeping the original form unchanged
文法句型
undergo a mutation
mutation in [system/structure]
用法筆記
This sense is formal and metaphorical. It describes a more dramatic and fundamental shift than ordinary words like 'change' or 'alteration.' Do not use it for everyday minor adjustments. Distinguish from sense 1 (biological process) — this sense applies only to non-biological subjects.