dedifferentiation
dedifferentiation — 名詞
1. a biological process in which mature, specialized cells lose their distinct char
去分化
成熟細胞失去特化功能,回到較原始狀態
a biological process in which mature, specialized cells lose their distinct characteristics and return to a simpler, less-developed form, often happening before a major structural change such as the regrowth of a damaged body part.
When a salamander loses a limb, some cells undergo dedifferentiation to form a regeneration bud.
當蠑螈失去肢體時,部分細胞會經歷去分化以形成再生芽基。
undergo dedifferentiation — verb + noun collocation in cell biology
Scientists observed dedifferentiation in plant cells after they were removed from the root tip.
科學家觀察到,從根尖分離後的植物細胞發生了去分化。
dedifferentiation in + [cell type] — common prepositional pattern
The study showed that dedifferentiation allows heart muscle cells to divide again after injury.
研究顯示,去分化能讓心肌細胞在受傷後再次分裂。
In the lab, researchers triggered dedifferentiation in skin cells by adding special proteins.
在實驗室中,研究人員透過添加特殊蛋白質,觸發了皮膚細胞的去分化。
- cellular reversion
more specific than dedifferentiation; emphasizes the return to an earlier cell state
- differentiation
the opposite process — cells becoming more specialized
用法筆記
This term is used almost exclusively in cell biology and developmental medicine. It describes the reverse of differentiation — cells becoming less specialized rather than more. The corresponding verb form (dedifferentiate) is also common in scientific writing.